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目的:观察麻杏二三汤联合西药治疗痰湿阻肺型小儿咳嗽的疗效及对免疫功能的影响。方法:选取91例咳嗽患儿作为研究对象,随机分为观察组与对照组。对照组45例采取常规综合治疗,观察组46例在对照组治疗基础上联用麻杏二三汤,对比2组的临床疗效、治疗前后的免疫功能指标(测定CD3与CD4)及不良反应发生情况。结果:观察组治疗总有效率为93.5%,高于对照组的77.8%,差异有统计学意义(P<0.05)。治疗前,2组CD3与CD4比较,差异均无统计学意义(P>0.05)。治疗后,2组CD3与CD4均较治疗前升高,差异均有统计学意义(P<0.05),观察组各时间点的CD3与CD4均高于对照组,差异均有统计学意义(P<0.05),提示观察组免疫功能恢复更快。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:麻杏二三汤联合西药治疗痰湿阻肺型小儿咳嗽具有较好疗效,同时利于患儿的免疫功能更快恢复。
Objective: To observe the curative effect of Muxing ErSang decoction combined with western medicine on phlegm-damp lung type pediatric cough and its effect on immune function. Methods: Ninety-one children with cough were selected as study subjects and randomly divided into observation group and control group. In the control group, 45 cases were treated by conventional combination therapy. 46 cases in the observation group were treated with Muxing ErSang decoction on the basis of the control group, and the clinical efficacy, immune function (CD3 and CD4) and adverse reactions before and after treatment were compared Happening. Results: The total effective rate of the observation group was 93.5%, which was higher than that of the control group (77.8%), the difference was statistically significant (P <0.05). Before treatment, there was no significant difference between the two groups in CD3 and CD4 (P> 0.05). After treatment, the CD3 and CD4 in both groups were significantly higher than those before treatment (P <0.05), and the CD3 and CD4 in the observation group were higher than those in the control group at each time point (P <0.05), suggesting that immune function in observation group recovered faster. The incidence of adverse reactions in the two groups, the difference was not statistically significant (P> 0.05). Conclusion: Maxing 23 soup combined with western medicine in the treatment of phlegm dampness-type children cough has a good effect, while conducive to the recovery of children’s immune function faster.