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目的:讨论视网膜母细胞瘤(Rb)复发、转移和病人死亡的原因,并提出在视网膜母细胞瘤诊治中的注意问题。方法:对1967年7月～1992年5月在我中心诊治的Rb病人中复发、转移和死亡的46例进行分析。结果:影响Rb预后的主要因素有:①是否早期诊断。②随着视神经受累程度的增加而死亡率增加。③Rb侵犯眼眶、颅脑和脉络膜。④临床上,Rb继发性青光眼通常伴视神经受累。结论:诊断和治疗的延误导致Rb复发、转移和患者死亡。因此,早期诊断和治疗是提高存活率的关键。眼科学报 1995;11:221—223。
OBJECTIVE: To discuss the causes of retinoblastoma (Rb) recurrence, metastasis and patient death, and put forward some problems in diagnosis and treatment of retinoblastoma. METHODS: Forty-six patients with recurrent, metastatic and fatal Rb in our hospital from July 1967 to May 1992 were analyzed. Results: The main factors affecting the prognosis of Rb are: ① whether early diagnosis. ② With the optic nerve involvement increased mortality increased. Rb violation of the orbit, brain and choroid. ④ clinically, Rb secondary glaucoma usually accompanied by optic nerve involvement. Conclusion: Delay in diagnosis and treatment lead to recurrence of Rb, metastasis and death of patients. Therefore, early diagnosis and treatment is the key to improve the survival rate. Journal of Ophthalmology 1995; 11: 221-223.