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致瘤性RNA病毒广泛分布于自然界,这些病毒按其形态或天然宿主可分为若干组。按一般规律,来自进化上相关种属的病毒的单股RNA基因组是同源的,因此它们的结构蛋白在生化上和抗元上是相关的,但不相同。因此水平式传播的鸡RNA肿瘤病毒与小鼠和猫的相应株不同,但是相关。 RNA肿瘤病毒感染并不导致细胞溶解,这是它的一种固有的优点,从而可以研究不同的和稳定的病毒-宿主细胞间的相互作用。根据所用的白血病病毒或肉瘤病毒,同种的细胞(天然宿主)或异种的细胞(其他宿主),病毒将复制或不将复制,引起或不引起恶性细胞转化。缺乏复制并不意味着感染病毒的消失,当
Oncogenic RNA viruses are widely distributed in nature, and these viruses can be divided into groups according to their morphology or native host. As a general rule, single-stranded RNA genomes from viruses that are evolutionarily related species are homologous, so that their structural proteins are biochemically and anti-metrelated, but not identical. The horizontal spread of the chicken RNA tumor virus is therefore related to the corresponding strains of mice and cats. RNA tumor virus infection does not lead to cell lysis, which is an inherent advantage of it, allowing the study of different and stable virus-host cell interactions. Depending on the leukemia virus or sarcoma virus used, cells of the same species (native host) or xenogeneic cells (other hosts), the virus will or will not replicate, cause or not cause malignant cell transformation. Lack of replication does not mean the disappearance of the infected virus