作者研究了胡椒碱对记忆和行为的作用,及其对神经递质(NA)、多巴胺(DA)和5-羟色胺(5-HT)的修饰作用。1)在急性毒性试验中,5组Wistar大鼠分别经口给予1、2、3、4和5g/kg胡椒碱,4h后观察行为改变。2)在十字迷宫试验中,Albino小鼠分成8组,每组5只。第1组为对照组,仅给赋形剂3d;第2 The authors studied the effects of piperine on memory and behavior, and its modification of neurotransmitters (NA), dopamine (DA) and serotonin (5-HT). 1) In the acute toxicity test, five groups of Wistar rats were orally given 1, 2, 3, 4 and 5 g/kg piperine, and the behavioral changes were observed after 4 hours. 2) In the cross labyrinth test, Albino mice were divided into 8 groups of 5 mice each. Group 1 was the control group, only given vehicle 3d;