同种异体排斥反应一直是阻碍器官移植发展的重要因素,诱导受体产生针对移植物的免疫耐受成为移植免疫学研究领域最富挑战性的课题之一。调节性T细胞(Treg)是一群具有免疫抑制作用的细胞,在诱导免疫耐受方面扮演着不可或缺的角色。随着科技的发展,对Treg研究的不断深入,人们试图利用其免疫调节作用对器官移植进行干预和治疗。本文重点综述了Treg在肝移植中的特点及作用。 Allogeneic rejection has been an important factor hindering the development of organ transplantation, and inducing immune tolerance of recipients to transplant has become one of the most challenging topics in the field of transplantation immunology. Regulatory T cells (Tregs) are a group of immunosuppressive cells that play an integral role in the induction of immune tolerance. With the development of science and technology, the research on Treg has been deepened. People try to use their immunomodulatory effects to intervene organ transplantation. This article focuses on the characteristics and role of Treg in liver transplantation.