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目的:了解高血压自发性脑出血患者在应用H_2受体拮抗剂预防急性应激性溃疡(SU)中的疗效。方法:采用随机选择43例高血压自发性脑出血病例除常规治疗外,加用H_2受体拮抗剂作为预防治疗,与既往高血压自发性脑出血未作预防治疗40例进行回顾性对比研究。结果:治疗组43例,并发SU者9例,对照组40例,并发SU者18例,明显高于治疗组(P<0.05)。结论:H_2受体拮抗剂在预防高血压自发性脑出血患者并发SU有确实效果。
Objective: To investigate the efficacy of H 2 receptor antagonist in the prevention of acute stress ulcer (SU) in patients with spontaneous hypertensive cerebral hemorrhage. Methods: Forty-three patients with spontaneous hypertensive cerebral hemorrhage were randomly selected and treated with H 2 receptor antagonist as prophylaxis. Forty-four patients with spontaneous intracerebral hemorrhage without prior prevention were compared retrospectively. Results: There were 43 cases in the treatment group, 9 cases complicated with SU, 40 cases in the control group and 18 cases complicated with SU, which were significantly higher than those in the treatment group (P <0.05). Conclusion: H 2 receptor antagonists have a positive effect on the prevention of concurrent SU in patients with spontaneous hypertensive cerebral hemorrhage.