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目的探讨印片细胞方法在乳腺肿瘤术中快速病理诊断的应用价值。方法对622例乳腺肿瘤手术标本分别进行印片细胞和快速石蜡切片检查,两者的诊断结果分别与常规石蜡切片诊断结果进行比较分析。结果印片细胞制片时间平均为5～8min,染色效果好,显示出肿瘤的分化特征;随着肿瘤恶性程度的增加,印片中细胞数量也明显增多;印片细胞和快速石蜡切片诊断准确性相近,分别为97.43%和99.04%,两者结合后乳腺肿瘤术中快速病理诊断的定性准确性可达到99.52%。结论术中乳腺印片细胞学诊断具有快速、准确、简便之优点,但有一定局限性,需要快速石蜡切片组织病理学诊断帮助。
Objective To explore the value of the method of printing cells in rapid pathological diagnosis of breast cancer. Methods Sixty-two cases of breast tumor specimens were examined by printing cells and rapid paraffin sections respectively. The diagnostic results of the two methods were compared with those of conventional paraffin sections. Results The average time of printing cells was 5 ~ 8min, the staining effect was good, which showed the differentiation characteristics of tumor. With the increase of the degree of malignancy, the number of cells in printing was significantly increased. The diagnostic accuracy of printing cells and rapid paraffin sections The similarities were 97.43% and 99.04%, respectively. The accuracy of the rapid pathological diagnosis of breast neoplasm combined with the two methods was 99.52%. Conclusion Intraoperative diagnosis of breast implants cytology has the advantages of fast, accurate and simple, but it has some limitations and needs the help of rapid paraffin section histopathology diagnosis.