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目的从文献计量角度分析1998-2008年血吸虫病研究的发展状况。方法以Web of Science引文数据库为检索对象,根据不同国家、机构和作者的发文量,文献被引频次和载文期刊的分布情况等方面分析1998-2008年国际和国内的血吸虫病研究热点。结果年度间文献发表量变化不大,美国在该领域具有绝对的领先优势,中国近年来的研究产出增长迅速,但与发达国家相比还有一定的差距。血吸虫病疫苗、药物开发及导致疾病的免疫机制方面的基础研究是国际上近几年的研究热点;日本血吸虫转录组和蛋白质组、日本血吸虫疫苗和药物、致病机制以及血吸虫病空间流行病学则是我国近几年的热点研究方向。结论近年来中国在血吸虫病研究领域发展较快,但与国际领先水平相比,还有一定差距。
Objective To analyze the development of schistosomiasis research from 1998 to 2008 from the perspective of bibliometrics. Methods Based on the Web of Science citation database, the hotspots of international and domestic schistosomiasis from 1998 to 2008 were analyzed according to the amount of published papers from different countries, institutes and authors, the distribution of citations and published articles. As a result, there was not much change in the published volume of the documents in the intervening years. The United States has an absolute leading edge in this field. The output of China’s research in recent years has seen rapid growth but still lags behind the developed countries. Schistosoma japonicum transcriptome and proteome, Schistosoma japonicum vaccines and drugs, pathogenic mechanism and space epidemiology of schistosomiasis are the basic research in the field of schistosomiasis vaccine, drug development and immune mechanism leading to disease. It is the hot research direction of our country in recent years. Conclusion China has witnessed rapid development in the field of schistosomiasis research in recent years, but there is still a certain gap compared with the international advanced level.