论文部分内容阅读
血小板粘附于血管壁的内皮下组织在血栓形成过程中起着重要作用。ＧＰＩｂ由ＧＰＩｂα和ＧＰＩｂβ两个亚单位组成。至今已发现ＧＰＩｂα基因多种不同的多态性位点 ,这些基因结构的变异是否改变或影响血小板功能目前尚不清楚 ,国外已有ＧＰＩｂα基因ＶＮＴＲ多态性与血栓性
Subendothelial tissue, where platelets adhere to the blood vessel wall, plays an important role in thrombus formation. GPIb consists of two subunits, GPIbα and GPIbβ. Up to now it has been found that many different polymorphic sites of GPIbα gene, whether the variation of these gene structure changes or affect the platelet function is not yet clear, there are foreign VNTR polymorphism of GPIbα gene and thrombosis