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内毒素休克是严重危害患者生命的急症之一,目前尚无特效药物治疗。近年来,我们以中药制剂牛珀至宝丹为主,治疗感染性休克取得明显疗效。为了探讨其作用机制,我们观察了该制剂对内毒素休克大鼠血清5-HT、组胺的影响。
Endotoxin shock is one of the acute diseases that seriously endanger the lives of patients. At present, there is no specific drug treatment. In recent years, we have made the traditional Chinese medicine preparation Niupo to Baodan, which has achieved remarkable curative effect in the treatment of septic shock. To investigate its mechanism of action, we observed the effects of the preparation on serum 5-HT and histamine in rats with endotoxin shock.