据纽约哥伦比亚大学的研究者报道,服用ACE(血管紧张素转换酶)抑制剂的美国病人可能剂量太低,以致不能达到显著改善病情和降低死亡率之目的。在临床实践中最常用的维持量是卡托普利25～50mg/d和2.5～5mg/d依那普利,与初始治疗量相似。据医生调查,这种模式基于两个未经证实的假设:(1)低剂量与高剂量一样有效,且几乎不产生副 Researchers at Columbia University in New York reported that U.S. patients taking ACE (angiotensin-converting enzyme) inhibitors may be too low to achieve the goal of significantly improving their condition and reducing their mortality. The most commonly used maintenance in clinical practice is captopril 25 ~ 50mg / d and 2.5 ~ 5mg / d enalapril, similar to the initial treatment. According to the doctor’s investigation, this model is based on two unconfirmed assumptions: (1) low doses are as effective as high doses and almost no side effects