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目的探讨低分子肝素与丹参注射液联合用药对早发型子前期(重度)的治疗效果。方法选取我院2008年10月至2012年10月诊断为重度子前期的患者共124例(孕龄在25～34周),随机平均分为四组,每组31例。第一组患者使用常规硫酸镁治疗,第二组患者使用硫酸镁加丹参注射液治疗,第三组患者使用硫酸镁加低分子肝素治疗,第四组患者使用硫酸镁、低分子肝素以及丹参注射液三种药物联合治疗,对比各组相关治疗结果的差异。结果第四组患者的孕龄延长时间和羊水量明显增加,脐动脉S/D值下降,新生儿体重明显增加,新生儿窒息率明显下降,与另外三组比较,差异有统计学意义(P<0.05)。同时第四组患者胎盘的重量有所增加,与第一组比较,差异有统计学意义(P<0.05),与另外两组比较差异无统计学意义。结论联合使用低分子肝素和丹参注射液在早发型的重度子前期治疗效果明显。
Objective To investigate the therapeutic effect of low molecular weight heparin combined with Salvia miltiorrhiza injection on the early (severe) premature molar. Methods A total of 124 patients (gestational age from 25 to 34 weeks) diagnosed as severe preeclampsia in our hospital from October 2008 to October 2012 were randomly divided into four groups (31 in each group). The first group of patients treated with conventional magnesium sulfate, the second group of patients treated with magnesium sulfate and Salvia injection, the third group of patients treated with magnesium sulfate plus low molecular weight heparin, the fourth group of patients with magnesium sulfate, low molecular weight heparin and Salvia injection Liquid three drugs combined treatment, comparing the differences between the treatment results for each group. Results The duration of gestational age and the amniotic fluid volume in the fourth group were significantly increased, the S / D value of the umbilical artery was decreased, the weight of neonates was significantly increased, and the asphyxia rate of newborns was significantly decreased. Compared with the other three groups, the difference was statistically significant (P <0.05). At the same time, the placenta weight of the fourth group patients increased, compared with the first group, the difference was statistically significant (P <0.05), with no significant difference compared with the other two groups. Conclusions Combined use of low molecular weight heparin and Salvia miltiorrhiza injection has obvious effect in the early treatment of severe hair follicles.