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目的探讨小剂量肝素辅助治疗儿童过敏性紫癜的临床效果。方法将患儿随机分为两组,对照组20例,采用常规综合治疗方法,观察组22例,在常规治疗的基础上加用小剂量肝素,对两组患儿临床疗效进行比较。结果观察组总有效率明显高于对照组(P<0.05);观察组临床症状改善时间比对照组明显缩短(P<0.05)。结论小剂量肝素疗法避免了使用大剂量时的诸多缺点,起效快、疗效显著,可作为儿童过敏性紫癜的辅助治疗药物临床推广应用。
Objective To investigate the clinical effect of low-dose heparin in the treatment of Henoch-Schonlein purpura in children. Methods The children were randomly divided into two groups, the control group of 20 cases, the use of conventional comprehensive treatment of 22 cases in the observation group, on the basis of conventional treatment with small doses of heparin, the clinical efficacy of the two groups were compared. Results The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The clinical symptom improvement time in the observation group was significantly shorter than that in the control group (P <0.05). Conclusion Low-dose heparin therapy avoids many shortcomings when using high-dose, has rapid onset and significant curative effect, and can be used as an adjunctive therapy for children with Henoch-Schonlein Purpura.