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Vein of Galen malformations (VGMs) are rare,consisting approximately 1% of intracranial vascular malformations,but nearly one third of pediatric vascular malformations,which can cause severe morbidity and mortality in infants and older children,but more particularly in neonates.We presented 2 patients with VGMs which were confirmed by characteristic clinical symptoms and neuroradiological findings (including CT,MRI and/or angiography).One patient underwent embolization followed by CT,MRI and conventional angiography.The patient’s neurological and cognitive status was normal at present.The other neonate died of congestive heart failure 36 h after birth.