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五味子是一种应用广泛的中药，可维持骨重建平衡，在促进成骨细胞分化、调控破骨细胞活性以及软骨保护等方面有重要作用，为骨质疏松、骨关节炎等疾病的治疗提供广阔前景。本文综述五味子及其活性成分在骨重建中的作用机制，以期为其产品开发及在骨组织工程中的应用提供理论依据。“,”Schisandra is a widely used herb in traditional Chinese medicine. It can maintain the balance of bone reconstruction and play an important role in promoting osteoblast differentiation, regulating osteoclast activity and protecting cartilage tissue. It provides a broad prospect for the treatment of osteoporosis, osteoarthritis and some other diseases. In this paper, the action mechanism of schisandra chinensis and its active components in bone reconstruction was reviewed in order to provide theoretical basis for its product development and application in bone tissue engineering.