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胃肠道恶性肿瘤的发生和演化是多因素参与、多步骤的进程 ,在其侵袭和转移过程时 ,基质金属蛋白酶 (MMP)起重要作用。MMP在胃癌侵袭和转移中起重要作用 ,有可能成为判断胃癌生物学行为的重要指标。MMP人工合成抑制剂的开发可能成为胃癌辅助治疗的手段。
The occurrence and evolution of gastrointestinal cancer is a multi-factor involved, multi-step process. Matrix metalloproteinases (MMPs) play an important role in the process of invasion and metastasis. MMP plays an important role in gastric cancer invasion and metastasis, which may become an important index to judge the biological behavior of gastric cancer. The development of MMP synthetic inhibitors may be a means of adjuvant therapy for gastric cancer.