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自从1963年发现乙型肝炎表面抗原以来,对乙型肝炎和乙型肝炎病毒(HBV)的研究日渐深入,不断取得进展。本文概述到1990年为止的国内外关于HBV标志物研究成果。一、HBV形态学的研究在电子显微镜下(放大12～15万倍),血液中的HBV颗粒至少可分为三类: (1)直径平均为22毫微米(nm)的小球形颗粒,是主要的HBsAg成分,可能是病毒的外壳。 (2)由小球形可能串连而成的管形颗粒,直径亦为22nm,长短不一(100～700nm),同样具有抗原性。
Since the discovery of hepatitis B surface antigen in 1963, the research on hepatitis B and hepatitis B virus (HBV) has been deepened and progressed. This article summarizes the research results of HBV markers at home and abroad till 1990. First, the study of HBV morphology Under the electron microscope (enlarged 12 to 150,000 times), HBV blood particles in the blood can be divided into at least three categories: (1) average diameter of 22 nm small spherical particles, is The main HBsAg component may be the virus’s shell. (2) Tubular particles that may be connected in series by small spheres are also 22nm in diameter and 100 ~ 700nm in length, which are also antigenic.