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目前胃癌依然是全球第五大恶性肿瘤，也是全球第二大癌症相关死亡原因。随着对胃癌的进一步认识，我们发现了一类EB病毒（EBV）感染的胃癌患者，经研究发现EBV阳性胃癌是一种独特的肿瘤，不仅具有独特的基因组畸变，而且具有明显的临床病理特征，预后较好。近年来，随着免疫治疗的发展，越来越多的研究表明运用免疫疗法治疗EBV阳性胃癌，有效率非常高。文章将对近年来EBV阳性胃癌的研究现状进行概述，从而为临床实践提供一定的参考。“,”Gastric cancer is still the fifth largest malignant tumor and the second largest cause of cancer-related death in the world. With the further understanding of gastric cancer, we found a kind of gastric cancer patients infected with EB virus (EBV). It is found that EBV-positive gastric cancer is a unique tumor, which not only has unique genomic aberration, but also has obvious clinicopathological features as well as a good prognosis. In recent years, with the development of immunotherapy, more and more studies have shown that immunotherapy for EBV-positive gastric cancer has a very high effective rate. This article summarizes the research status of EBV-positive gastric cancer in recent years, so as to provide some reference for clinical practice.