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为了研究全胃切除、胃及幽门重建新术式及术后胃癌患者免疫功能的变化,测定了胃癌患者术后0.5a、1a血液中IgA、IgG、IgM、CD4、CD8、NKL、L、IL-2、sIL-2R、INF-γ水平。新术式术后患者IgA、IgG、IgM、CD4、NKL、L、IL-2、INF-γ水平明显高于传统术式组(P<0.01),与非肿瘤手术组相比无显著性差异(P>0.05);新术式术后患者CD8、sIL-2R水平明显低于传统术式组(P<0.01),与非肿瘤手术组相比无显著性差异(P>0.05)。结果提示,新术式患者术后免疫功能恢复较快,而传统术式患者术后免疫功能恢复较慢且低下。
In order to study the changes of total gastrectomy, gastric and pyloric reconstruction procedures, and the immune function of patients with postoperative gastric cancer, IgA, IgG, IgM, CD4, CD8, NKL, and L in blood of patients with gastric cancer 0.5a and 1a after surgery were measured. IL-2, sIL-2R, INF-γ levels. The levels of IgA, IgG, IgM, CD4, NKL, L, IL-2, and INF-γ in patients after the new operation were significantly higher than those in the traditional operation group (P<0.01), and they were not significant compared with the non-tumor operation group. Sex differences (P>0.05); The levels of CD8 and sIL-2R in patients after new operation were significantly lower than those in the traditional operation group (P<0.01), and there was no significant difference compared with the non-tumor operation group (P >0.05). The results suggest that the recovery of the immune function of the new surgical patients is faster, while the recovery of the immune function after the traditional surgical patients is slow and low.