我们既往的研究表明 [1,2 ] ,抗纤软肝冲剂对于肝硬变患者和实验性肝纤维化大鼠 ,都具有良好的治疗作用。本实验采用血清药理学方法 ,观察该方对肝星状细胞 ( HSC)增殖和胶原合成的影响 ,从细胞学水平探讨该方抗肝纤维化的作用机理。1　材料和方法1 .1　材料1 .1 .1　动物　 Wi Our previous studies have shown that [1,2], anti-fibrosis liver granules for cirrhosis patients and experimental liver fibrosis in rats, have a good therapeutic effect. In this experiment, serum pharmacological methods were used to observe the effects of this prescription on the proliferation and collagen synthesis of hepatic stellate cells (HSCs). The mechanism of the anti-hepatic fibrosis was explored from the cytological level. 1 Materials and Methods 1.1 Materials 1 .1 Animal Wi