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目的探讨短期胰岛素强化治疗对初诊血糖较高的2型糖尿病患者的疗效。方法选取2014年6月至2016年6月江苏省江阴市长寿医院收治的初诊血糖较高的2型糖尿病患者60例为研究对象,随机将其分为观察组和对照组,每组30例。对照组患者采用一般降糖治疗方案治疗,观察组患者采用胰岛素强化治疗方案治疗,比较两组患者临床疗效、空腹血糖(FPG)、餐后2 h血糖(2hPBG)、糖化血红蛋白(HbA1c)、三酰甘油(TG)水平及血糖达标时间。结果观察组患者治疗的总有效率达93.3%,显著高于对照组的73.3%,差异有统计学意义(P<0.05);治疗后观察组患者FPG、2hPBG、HbA1c、TG均明显低于对照组,血糖达标时间明显短于对照组,差异均有统计学意义(均P<0.05)。结论短期胰岛素强化治疗对于初诊血糖较高的2型糖尿病的效果显著,能够在短期内使血糖得到满意控制,并改善血脂水平。
Objective To investigate the efficacy of short-term insulin-intensive therapy in newly diagnosed type 2 diabetic patients with high blood sugar. Methods From June 2014 to June 2016, 60 patients with newly diagnosed type 2 diabetes in Changshou Hospital, Jiangyin City, Jiangsu Province were selected as study subjects and randomly divided into observation group and control group, 30 cases in each group. The patients in the control group were treated with general hypoglycemic regimen. The patients in the observation group were treated with intensive insulin therapy. The clinical effects, fasting blood glucose (FPG), postprandial blood glucose (2hPBG), HbA1c, Acylglycerol (TG) levels and blood glucose compliance time. Results The total effective rate of observation group was 93.3%, which was significantly higher than that of control group (73.3%), the difference was statistically significant (P <0.05). After treatment, FPG, 2h PBG, HbA1c and TG in observation group were significantly lower than those in control group Group, blood glucose compliance time was significantly shorter than the control group, the differences were statistically significant (P <0.05). Conclusion Short-term intensive insulin therapy has a significant effect on newly diagnosed type 2 diabetes with high blood sugar, which can control blood sugar in a short period of time and improve blood lipid level.