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测定了40例秋季腹泻患儿急性期和恢复期外周血T细胞亚群和红细胞免疫功能,与同龄正常儿童比较。结果表明急性期患儿CD3、CD4细胞及CD4/CD8细胞比值明显降低,CD8不变,红细胞C_3b受体花环也显著下降。随着临床症状的恢复,CD3、CD4、CD4/CD8细胞比值及红细胞C_3b受体花环率也逐渐正常。提示细胞免疫参与了感染过程,CD4/CD8细胞比值与疾病预后有关。秋季腹泻急性期有继发性红细胞免疫功能下降,治疗时有必要调节患儿的红细胞免疫功能,提高抗感染能力。
The peripheral blood T lymphocyte subsets and erythrocyte immune function in 40 children with autumnal diarrhea were measured at acute and convalescent stages, compared with normal children of the same age. The results showed that the ratio of CD3, CD4 and CD4 / CD8 in children with acute stage was significantly lower, CD8 unchanged, and the rosette of erythrocyte C_3b receptor was significantly decreased. With the recovery of clinical symptoms, the ratio of CD3, CD4, CD4 / CD8 cells and R C3 red blood cell rosette rate gradually became normal. Prompted cellular immunity involved in the process of infection, CD4 / CD8 cell ratio and disease prognosis. Autumn diarrhea acute erythrocyte immune function decline in the treatment of children with the need to regulate red blood cell immune function and improve anti-infective ability.