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患者女,21岁。因颈部淋巴结肿大,自行口服网上所购中药“七络丹”8个月,双手足丘疹、颜面颈部躯干色素沉着5个月。查体:双手足见多个密集分布的角化性丘疹,约小米粒大小;颜面、颈部、躯干见大片棕褐色色素沉着,界不清。皮损组织病理检查示:表皮角化过度,真皮浅层慢性炎症细胞浸润和小血管扩张。尿砷22.10μmol/L。诊断:中药致慢性砷中毒。经硫代硫酸钠治疗后,丘疹和色素沉着明显减退。
Female patient, 21 years old. Due to cervical lymph node enlargement, self-purchased online purchase of Chinese medicine “seven network Dan ” for 8 months, hands and feet pimples, facial neck pigmentation pigmentation 5 months. Examination: both hands showed a number of densely distributed keratosis papules, about the size of the grain; face, neck, trunk see large tan pigmentation, unclear. Histopathological examination of the lesion revealed epidermal hyperkeratosis, superficial chronic dermal infiltration and small vessel dilatation. Urinary arsenic 22.10μmol / L. Diagnosis: Chronic arsenic poisoning caused by Chinese medicine. After treatment with sodium thiosulfate, papules and pigmentation significantly decreased.