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目的观察帕金森病患者疼痛的临床治疗效果。方法选取2015年2月-2016年2月医院收治帕金森病患者88例作为研究对象,随机分为观察组和对照组,每组44例。对照组采用美多芭进行治疗,观察组采用度洛西汀进行治疗,观察比较2组患者治疗前后的疼痛评分情况以及临床治疗效果。结果 2组治疗后的疼痛评分均比治疗前有所下降(P<0.01),观察组的下降幅度大于对照组(t=10.13,P<0.01)。治疗总有效率观察组为88.64%,高于对照组的70.45%(χ~2=4.47,P<0.05),差异具有统计学意义。结论治疗帕金森病患者的有效药物为度洛西汀,该药物能够有效缓解患者的肌肉关节疼痛症状,促进患者康复,从而提高患者的生活质量,值得临床推广应用。
Objective To observe the clinical effect of pain in patients with Parkinson’s disease. Methods From February 2015 to February 2016, 88 patients with Parkinson’s disease in our hospital were selected as study subjects and randomly divided into observation group and control group with 44 cases in each group. The control group was treated with metoprolol, the observation group was treated with duloxetine, and the pain score and clinical treatment effect before and after treatment in the two groups were observed and compared. Results The scores of pain after treatment in both groups were significantly lower than those before treatment (P <0.01). The decrease in the observation group was greater than that in the control group (t = 10.13, P <0.01). The total effective rate in the observation group was 88.64%, which was higher than 70.45% in the control group (χ ~ 2 = 4.47, P <0.05). The difference was statistically significant. Conclusions Duloxetine, an effective drug for the treatment of Parkinson’s disease, can effectively relieve the symptoms of muscle and joint pain, promote the rehabilitation of patients and improve the quality of life of patients. It is worthy of clinical application.