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Objective:Diagnosis of atypical pathogens as an aetiology for community-acquired pneumonia(CAP) in children is a challenge world wide.The aim of this study was to detect the frequency of atypical pathogens as a cause of community-acquired pneumonia(CAP) in Egyptian children.Methods:From 50 children(with age ranged from 2 months to 12 years) hospitalized for community-acquired pneumonia;respiratory sputum samples were collected by induction or spontaneously.All samples were subjected to conventional cultures and Polymerase Chain Reaction(PCR) technique DNA extraction for identification of Mycoplasma,Chlamydia pneumoniae and Legionella pneumophila.Results;A definite pathogen was identified in 78%of the studied children;30% typical bacteria,8%Candida albicans and atypical bacteria in 40%of the pneumonic children.Chlamydia pneumoniae was isolated from 26%of the children while Mycoplasma pneumoniae was isolated from 14%, whereas Legionella pneumophilla was not isolated at all.Conclusion;Atypical pathogens are evident as a potential aetiology for community-acquired pneumonia in(13.3%) of young and(80%) of older Egyptian children.
Objective: Diagnosis of atypical pathogens as an aetiology for community-acquired pneumonia (CAP) in children is a challenge world wide. The AIM of this study was to detect the frequency of atypical pathogens as a cause of community-acquired pneumonia (CAP) in Egyptian children. Methods: From 50 children (with age ranged from 2 months to 12 years) hospitalized for community-acquired pneumonia; respiratory sputum samples were collected by induction or spontaneously. All samples were subjected to conventional cultures and Polymerase Chain Reaction (PCR) Methods DNA extraction for identification of Mycoplasma, Chlamydia pneumoniae and Legionella pneumophila. Results; A definite pathogen was identified in 78% of the studied children; 30% typical bacteria, 8% Candida albicans and atypical bacteria in 40% of the pneumonic children. Chlamydia pneumoniae was isolated from 26% of the children while Mycoplasma pneumoniae was isolated from 14%, while Legionella pneumophilla was not isolated at all .Conclusion; Aty pical pathogens are evident as a potential aetiology for community-acquired pneumonia in (13.3%) of young and (80%) of older older children.