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本文对30例AMI患者进行了红细胞膜钠泵活性（SPA）测定，同时测血脂质过氧化物（MDA）、超氧化物歧化酶（SOD）。结果证明AM时SPA（0、23±0、05）明显低于对照组（0．57±0．04，P＜0．001）和不稳定心绞痛组（0、45±0．06，P＜0、005），AMI组MDA（3、80±0.48）高于对照组（2．51±0．43，P＜0．001），SOD（1345、03±244、44）低于对照组（1631、80±163、91，P＜0、001）；SPA与MDA呈负相关（r=0．36，P＜0、05），与SOD呈正相关（r＝0、49，P＜0、05）；溶栓治疗后MDA增加，SPA降低，且两者间的改变具高度相关性（r=0、78，P＜0．001）证明氧自由基可能对AMI时的钠泵损伤起作用。
In this paper, 30 cases of AMI patients were measured erythrocyte membrane sodium pump activity (SPA) determination, at the same time measuring blood lipid peroxide (MDA), superoxide dismutase (SOD). The results showed that SPA (0,23 ± 0,05) was significantly lower than that of the control group (0.57 ± 0.04, P <0.001) and unstable angina group (0,45 ± 0.06, P < 0,005). The levels of MDA (3,80 ± 0.48) in AMI group were significantly higher than those in control group (2.51 ± 0.43, P <0.001), and SOD (1345,03 ± 244,44) (R = 0.36, P <0.05). There was a positive correlation between SOD and MDA (r = 0, 49, P <0, 05). MDA increased and SPA decreased after thrombolytic therapy, and there was a high degree of correlation between them (r = 0, 78, P <0.001). It was demonstrated that oxygen free radicals may play a role in sodium pump injury during AMI .