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目的:探讨馥感啉口服液治疗小儿感染相关性中性粒细胞减少症的疗效。方法:选择40例小儿感染相关性粒细胞减少症患儿,采用简单随机法分为A组(馥感啉组)20例,B组(鲨肝醇组)20例,对比A、B组患者治疗后外周血中性粒细胞升至正常、发热及感冒症状改善时间的变化。结果:治疗7天后,A组患者总有效率为95.0%,优于B组的70.0%,差异具有统计学意义(P<0.05)。A组患者退热时间、感冒症状改善时间短于B组患者,两组比较差异有统计学意义(P<0.05),而中性粒细胞复常时间比较差异无统计学意义(P>0.05)。结论:馥感啉口服液治疗小儿感染相关性粒细胞减少症效果明显,能有效缩短症状缓解时间,值得临床推广应用。
Objective: To investigate the efficacy of Fukailin oral solution in the treatment of infection-related neutropenia in children. Methods: Forty infants with infection-related neutropenia were selected and randomly divided into 20 cases in group A (group B) and 20 cases in group B (shark liver alcohol group). Compared with group A and group B Peripheral blood neutrophil rose to normal after treatment, fever and cold symptoms to improve the time changes. Results: After 7 days of treatment, the total effective rate in group A was 95.0%, which was better than that in group B 70.0%. The difference was statistically significant (P <0.05). A group of patients with antipyretic time, cold symptom improvement time is shorter than the B group, the difference between the two groups was statistically significant (P <0.05), while the neutrophil recovery time was no significant difference (P> 0.05) . CONCLUSION: FuXinLin Oral Liquid is effective in treating childhood infection-related neutropenia and can effectively shorten the time for symptom relief, which is worthy of clinical application.