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本文对6例异常Pi表型和3例正常Pi表型尸检病人的肾脏组织作了免疫组化研究,以显示α-1-抗胰蛋白酶(α-1-AT)。结果显示,全部正常Pi表型病人肾小管上皮细胞对α-1-AT染色呈阳性反应。与此相反,6例异常Pi表型病人中,1例反应阴性,4例仅部分近曲小管阳性,仅1例肾脏有较多阳性反应肾曲小
In this paper, immunohistochemistry was performed on 6 cases of abnormal Pi phenotype and 3 cases of normal Pi phenotype autopsy patients to show α-1-antitrypsin (α-1-AT). The results showed that all normal Pi phenotype of renal tubular epithelial cells positive for α-1-AT staining. In contrast, one of six abnormal Pi phenotype patients was negative, only four of them were mostly proximal tubule-positive and only one of them had more positive reactions.