Minerals of spinel- and garnet-facies mantle xenoliths entrained in Cenozoic basalts from eastern China (North China, Northeastern China and Southeastern China coastal area) contains lots of melt inclusions. Studies on these melt inclusions show that the glass inclusions are rich in SiO2 (60%―68%) and alkalis (K2O+Na2O=5%―11%, especially for K2O) as well as volatiles such as H2O and CO2 (2%―7%), which belong to dacites and andesites of the high-K calcic alkali series rocks with few shoshonites. High Al and Ca diopside in melt inclusion is the product of melt crystallization at high temperature and pressure, rather than the product of devitrification. Results show that these K-rich (in general K2O>3%) intermediate-acidic silicate melt inclusions have characteristics of continent without a genetical link to host basalts and their phenocrystic minerals. Thus, these trapped melt inclusions represent melts of Mesozoic lithospheric mantle-crust interaction and imply that the continental litho-spheric mantle beneath eastern China had undergone fragmentation and recreation processes during the Mesozoic and Cenozoic periods. This result undoubtly provides important implication for the evo-lution of sub-continental lithosphere beneath eastern China. We propose that these Si- and alka-lis-rich melts should be responsible for the mantle chemical heterogeneity underneath eastern China. Minerals of spinel- and garnet-facies mantle xenoliths entrained in Cenozoic basalts from eastern China (North China, Northeastern China and Southeastern China coastal area) contains lots of melt inclusions. Studies on these melt inclusions show that the glass inclusions are rich in SiO2 ( 60% -68%) and alkalis (K2O + Na2O = 5% -11%, especially for K2O) as well as volatiles such as H2O and CO2 (2-7%), which belong to dacites and andesites of the high- K calcic alkali series rocks with few shoshonites. High Al and Ca diopside in melt inclusion is the product of melt crystallization at high temperature and pressure, rather than the product of devitrification. Results show that these K-rich (in general K2O> 3% ) intermediate-acidic silicate melt inclusions have characteristics of continent without a genetical link to host basalts and their phenocrystic minerals. Thus, these trapped melt inclusions represent melts of Mesozoic lithospheric mantle-crust interaction and imply that the continenta l litho-spheric mantle beneath eastern China had undergone fragmentation and recreation processes during the Mesozoic and Cenozoic periods. This result undoubtly provides important implication for the evo-lution of sub-continental lithosphere beneath eastern China. We propose that these Si- and alka- lis-rich melts should be responsible for the mantle chemical heterogeneity underneath eastern China.