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评价左旋氧氟沙星（LVFX）治疗细菌性感染的疗效与安全性。治疗病种包括下呼吸道、尿路、服道、创伤、烧伤感染、伤寒及淋病共205例。在下呼吸道及尿路感染中，以LVFX和阿莫西林／克拉维酸（Amoxi／Clav）作对照。结果均以LVFX组的疗效明显优于Amoxi／Clav组。用LVFX治疗145例的总有效率为93．1％，细菌清除率为91．2％。药敏试验示大多数病原菌对LVFX是敏感的，且与临床疗效相符合。LVFX300mgl次口服后的血、尿药浓度均超过大多数病原菌的最小抑菌浓度（MIC），达到有效抗菌作用。LVFX的不良反应少且轻微，说明LVFX治疗细菌性感染安全有效。
To evaluate the efficacy and safety of levofloxacin (LVFX) in the treatment of bacterial infections. Treatment of diseases including lower respiratory tract, urinary tract, service road, trauma, burn infection, typhoid and gonorrhea a total of 205 cases. In the lower respiratory and urinary tract infections, LVFX and amoxicillin / clavulanate (Amoxi / Clav) were used as controls. The results were significantly better than the LVFX group Amoxi / Clav group. The total effective rate of the treatment of 145 cases with LVFX was 93.1% and the bacterial clearance rate was 91.2%. Susceptibility testing showed that most pathogens were sensitive to LVFX and consistent with clinical efficacy. LVFX300mgl times after oral administration of blood, urine concentrations exceed the minimum inhibitory concentration (MIC) of most pathogens to achieve effective antibacterial effect. Adverse reactions to LVFX were mild and mild, indicating that LVFX is safe and effective in the treatment of bacterial infections.