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应用酶联免疫法测定５７例消化道肿瘤患者血清中胃肠道癌抗原（ＧＣＡ）浓度，以３７ｕ／ｍｌ为阳性界限值，测得消化道肿瘤ＧＣＡ阳性率５４．４％，其中胃癌５５．２％，肠癌５４．５％，食管癌２５％，肝癌６６．７％，而非消化道癌阳性率５．６％，正常人阳性率为５．０％。对９例消化道癌患者化疗前后ＧＣＡ变化的分析表明，ＧＣＡ水平的提高可预示病情的进展。提示ＧＣＡ可作为消化道肿瘤的辅助诊断指标及预后参考指标。
The concentration of gastrointestinal cancer antigen (GCA) in serum of 57 patients with digestive tract cancer was measured by enzyme-linked immunosorbent assay. The positive limit of GCA was 37u/ml. The positive rate of GCA in digestive tract tumors was 54.4%. Gastric cancer was 55. 2%, colon cancer 54.5%, esophageal cancer 25%, liver cancer 66.7%, non-digestive cancer positive rate 5.6%, normal positive rate was 5.0%. The analysis of changes in GCA before and after chemotherapy in 9 patients with digestive tract cancer showed that the increase of GCA level may indicate the progression of the disease. It is suggested that GCA can be used as an auxiliary diagnosis index and prognosis reference index of digestive tract tumors.