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采用自行研制的平均粒径56.3μm的顺铂-白蛋白微球(CDDP-AMS)100mg(含CDDP13.6mg),经舌动脉灌注治疗舌部鳞癌患者11例,临床及病理观察,灌注后4周的病理标本已无癌巢及确切散在癌细胞,灌注后5~6周临床肿瘤创面已消失,但因患侧舌体有纤维组织形成,难于判定肿瘤瘤体变化,通过4例在灌注后未行瘤体切除病例半年以上观察,肿块消失,舌体柔软。提示本法可作为舌癌综合治疗行之有效的方法之一
A total of 11 patients with lingual squamous cell carcinoma were treated with oral administration of 100 mg of CDDP-AMS (CDDP-AMS) with an average diameter of 56.3 μm. The clinical and pathological findings, perfusion After 4 weeks of pathological specimens have no cancer nests and the exact scattered in cancer cells, 5 to 6 weeks after perfusion of clinical tumor wound has disappeared, but due to ipsilateral tongue body fibroids, it is difficult to determine changes in tumor ontology, through 4 cases in Not perfusion after resection of the tumor more than half a year of observation, the mass disappeared, the tongue soft. Prompted this method can be used as one of the effective methods of tongue cancer comprehensive treatment