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目的:研究乙二胺四乙酸铁钠(NaFeEDTA)口服液治疗婴幼儿缺铁性贫血及对血铅水平的影响。方法:对101例缺铁性贫血(IDA)的患儿给予NaFeEDTA口服液,0.5mg·kg~(-1)·d~(-1),连服8周,治疗前后分别测定血常规和血铅,并与正常儿童对照。结果:用药8周后93.0%患儿血红蛋白(Hb)恢复至正常水平(P<0.01);治疗前IDA患儿血铅均较正常儿童高(P<0.05),治疗8周后血铅较治疗前明显降低(P<0.05)。结论:NaFeEDTA口服液治疗婴幼儿IDA临床效果好,可显著降低血铅水平。
Objective: To study the effect of NaFeEDTA oral solution on iron deficiency anemia in infants and young children and on blood lead levels. Methods: 101 cases of iron deficiency anemia (IDA) were given NaFeEDTA oral solution, 0.5mg · kg -1 (-1) d -1, even for 8 weeks, before and after treatment were determined blood and blood Lead, and with normal children control. Results: After 8 weeks of treatment, hemoglobin (Hb) returned to normal in 93.0% of children (P <0.01). Before treatment, the blood lead of IDA children was higher than that of normal children (P <0.05) Before significantly reduced (P <0.05). Conclusion: NaFeEDTA oral solution for infants and young children IDA clinical effect, can significantly reduce blood lead levels.