论文部分内容阅读
目的:探讨灯盏花素注射液对儿童病毒性心肌炎(VMC)心率减速力(DC)的影响。方法:将70例病毒性心肌炎患儿随机分为治疗组40例和对照组30例。治疗组给予灯盏花素注射液10 mg加入5%葡萄糖注射液250 mL静脉滴注;对照组给予辅酶A 100 U、ATP 40 mg加入5%葡萄糖注射液250 mL静脉滴注,疗程均为14 d。对所有患儿治疗前后进行24 h动态心电图监测,应用DC处理软件,离线计算DC值。结果:治疗组治疗后DC值明显升高,与治疗前比较差异有统计学意义(P<0.01);两组治疗后DC值及CK-MB值比较差异有统计学意义(P<0.01)。结论:病毒性心肌炎患儿伴有迷走神经功能受损,灯盏花素注射液可改善迷走神经功能,对心肌有保护作用。
Objective: To investigate the effect of breviscapine injection on heart rate deceleration (DC) in children with viral myocarditis (VMC). Methods: 70 children with viral myocarditis were randomly divided into treatment group 40 cases and control group 30 cases. The treatment group was given breviscapine injection 10 mg 5% glucose injection 250 mL intravenous infusion; the control group coenzyme A 100 U, ATP 40 mg 5% glucose injection 250 mL intravenous infusion, the course of treatment for 14 d . All patients were monitored 24 hours before and after treatment with electrocardiogram, and DC software was used to calculate the DC value offline. Results: After treatment, the DC value in treatment group was significantly higher than that before treatment (P <0.01). There was significant difference in DC value and CK-MB value between two groups after treatment (P <0.01). Conclusion: Children with viral myocarditis have impaired vagal function. Breviscapine injection can improve vagal function and protect myocardium.