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对６４例复发性消化性溃疡（ＲＰＵ）患者幽门螺旋杆菌（ＨＰ）进行检测，发现ＨＰ的阳性检出率为９６．９％，明显高于初发溃疡（８４．５％）患者（Ｐ＜０．０５），且以复发性十二指肠球部溃疡（ＲＤＵ）ＨＰ的阳性检出率居高，表明ＨＰ与ＲＰＵ的关系密切。经用雷尼替丁１５０ｍｇ，每日２次，加甲硝唑０．２ｇ，在日３次，治疗２个疗程后，溃疡愈合率和ＨＰ阴转率分别为９２％和６６％，均取得较为满意的效果。本研究还提示，溃疡愈合后，防止溃疡复发而服用抑酸剂的同时加用杀灭ＨＰ的抗生素是必要的。
The detection of Helicobacter pylori (HP) in 64 patients with recurrent peptic ulcer (RPU) found that the positive detection rate of HP was 96.9%, which was significantly higher than that of the patients with primary ulcer (84.5%) (P < 0.05), and the positive detection rate of recurrent duodenal ulcer (RDU) HP was high, indicating that HP and RPU are closely related. With ranitidine 150mg, 2 times a day, plus metronidazole 0.2g, 3 times a day, after 2 courses of treatment, ulcer healing rate and HP negative conversion rate were 92% and 66%, were achieved More satisfied with the results. This study also suggests that ulcer healing, to prevent the recurrence of ulcers while taking acid suppressant plus antibiotics to kill HP is necessary.