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为评价溶栓治疗后QTcd的动态变化,我们对46例首次急性心肌梗死接受静脉溶栓者测定QTc、QTcd及QTcdc。结果发现溶栓成功者(n=32)与溶栓失败者(n=14)QTcd及QTcdc在溶栓治疗前无明显变化。但在溶栓治疗后2小时、8小时、24小时,1周及4周时的QTcd及QTcdc在溶栓成功者较失败者明显下降。但二组病人之QTc无明显差异。成功溶栓治疗后QTcd下降可能是其预后改善的重要机制之一。
To assess the dynamic changes of QTcd after thrombolytic therapy, we measured QTc, QTcd and QTcdc in 46 patients with first acute myocardial infarction receiving intravenous thrombolysis. The results showed no significant change in QTcd and QTcdc before thrombolytic therapy in patients with successful thrombolysis (n = 32) and those with failed thrombolysis (n = 14). However, QTcd and QTcdc at 2, 8, 24, 1 and 4 weeks after thrombolytic therapy were significantly lower than those with failed thrombolysis. However, there was no significant difference in QTc between the two groups. QTcd decline after successful thrombolytic therapy may be one of the important mechanisms of its prognosis.