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目的探讨儿童急性白血病并发侵袭性肺曲霉菌病(IPA)的CT特征。方法回顾性分析经临床和痰培养证实的13例IPA患儿的临床、CT资料,13例均行胸部CT扫描,并进行了4～10次随访CT扫描。结果首次CT表现:单发结节2例,多发结节影10例,结节伴晕征9例,胸膜下楔形实变影5例,其中4例胸膜下楔形实变影与肺部多发结节影并存。随访CT扫描结节病灶和楔形病灶内出现空洞或“空气新月征”11例,7例结节病灶和2例空洞病灶周围出现晕征。结论IPA的CT表现具有一定的特征性,CT对观察该病的发展、演变及估计预后有重要的价值。
Objective To investigate the CT features of children with acute leukemia complicated with invasive pulmonary aspergillosis (IPA). Methods The clinical data and CT data of 13 children with IPA confirmed by clinical and sputum culture were retrospectively analyzed. Thirteen patients underwent CT scan of the thorax and 4 to 10 follow-up CT scans. Results The first CT showed single nodules in 2 cases, multiple nodules in 10 cases, nodules with halo sign in 9 cases, subpleural wedge consolidation in 5 cases, of which 4 cases of subpleural wedge consolidation and lung multiple consolidation knot Festival co-exist. Follow-up CT scan nodules and wedge-shaped lesion cavity or “air crescent sign” in 11 cases, 7 cases of nodular lesions and 2 cases of hollow lesions around the halo sign. Conclusion The CT findings of IPA have certain characteristics. CT is of great value in observing the development, evolution and prognosis of this disease.