骨髓增生异常综合征(MDS)是一组异源性血液系统疾患,其中难治性贫血(RA)和伴环形铁粒幼细胞增多的难治性贫血(RARS)转变成急性白血病者不多,但伴原始细胞过多的难治性贫血(RAEB)、转化中的伴原始细胞过多的难治性贫血(RAEB-T)和慢性粒单细胞白血病(CMML)却常见。近年来曾经用不同方法治疗 MDS,但疗效不佳,治疗通常是靠频繁输血。最近有一些用重组人红细胞生成素(rhEPO)治疗的报道。作者报道了用 rhEPO 治疗3例 CMML 转变为急性白 Myelodysplastic syndrome (MDS) is a group of hereditary hematological disorders in which rare patients with refractory anemia (RA) and refractory anemia (RARS) with an increase in mitochondrial erythroblasts become acute leukemias, However, refractory anemia with excess blasts (RAEB), transformed refractory anemia with excess blasts (RAEB-T) and chronic myelomonocytic leukemia (CMML) are common. In recent years, different methods have been used to treat MDS, but the curative effect is poor. The treatment is usually based on frequent transfusions. Recently there have been some reports of treatment with recombinant human erythropoietin (rhEPO). The authors reported that rhEPO treatment of 3 cases of CMML into acute white