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目的:探讨宫颈小细胞癌(SCCC)的临床病理特点、诊断、治疗和预后。方法:通过回顾分析2011年6月中国人民解放军海军总医院收治的1例SCCC患者的临床资料,探讨其临床病理特征及预后。结果:患者为55岁绝经后女性,临床表现为绝经后接触性阴道出血,伴右侧腰部胀痛。患者出现症状半年后于当地医院就诊,见宫颈异常肿物,病理活检提示为SCCC。我院病理会诊结果仍为SCCC,超声及肺部CT影像学检查提示,肺部转移及宫旁浸润,压迫右侧输尿管。患者按EP方案给予化疗1次,于2012年5月死亡。结论:SCCC癌恶性度高,预后差,死亡率高。其确诊主要依靠病理组织形态学和免疫组化。目前多采用手术、化疗和放疗联合综合治疗。
Objective: To investigate the clinicopathological features, diagnosis, treatment and prognosis of cervical small cell carcinoma (SCCC). Methods: The clinical data of one SCCC patient admitted to PLA Navy General Hospital of Chinese People's Liberation Army in June 2011 were retrospectively analyzed to investigate the clinicopathological characteristics and prognosis. Results: The patient was a 55-year-old postmenopausal woman with clinical manifestations of post-menopausal vaginal bleeding with right lower back pain. Six months after the onset of symptoms in a local hospital, see cervical abnormalities, pathological biopsy prompted SCCC. The results of pathological consultation in our hospital is still SCCC, ultrasound and pulmonary CT imaging examination prompted lung metastasis and uterine infiltration, oppression of the right ureter. The patients were given chemotherapy once according to EP regimen and died in May 2012. Conclusion: SCCC has high malignancy, poor prognosis and high mortality. The diagnosis depends mainly on histopathology and immunohistochemistry. Currently more use of surgery, chemotherapy and radiotherapy combined with comprehensive treatment.