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目的探究国家免费孕前优生健康检查对出生缺陷一级预防的临床意义。方法回顾性分析本区2012年6月-2016年12月接受国家免费孕前优生健康检查的人群的筛查情况,对筛查出的高风险人次进行统计,对男女高风险人群的高风险因素进行分析。结果 2012年6月-2016年12月本区共进行国家免费孕前优生健康检查14366人次,其中男方6738人次,女方7628人次,检查前曾接受过专业优生宣传培训的占12.62%,筛查出高风险人群共计1710人次,其中男方高风险为492人次,女方高风险为1218人次,高风险发生率为11.90%。女方高风险因素中以甲状腺功能异常、血糖增高、贫血、习惯性流产和有过不良妊娠结局史者居多。男方高风险疾病以转氨酶增高和艾滋病居多。这些疾病孕前进行保健指导和治疗可有效减少出生缺陷。结论国家免费孕前优生健康检查是出生缺陷一级干预的重要手段,有助于提高围产期的保健质量,值得进一步应用和推广。
Objective To explore the clinical significance of national primary prenatal health checkup for primary prevention of birth defects. Methods Retrospective analysis of the screening of the population of the national free pre-pregnancy eugenics checkup from June 2012 to December 2016 in this area, and the statistics of the high-risk persons screened out, and the high risk factors of high risk men and women analysis. Results From June 2012 to December 2016, a total of 14366 health check-ups for pre-pregnancy eugenics were conducted in the district, including 6738 men and 7628 women, 12.62% of whom had received professional eugenics training prior to the examination. The total number of risk groups was 1710, with 492 high-risk men and 1218 high-risk women. The high-risk rate was 11.90%. High risk factors in women with thyroid dysfunction, elevated blood sugar, anemia, habitual abortion and had a history of adverse pregnancy outcomes mostly. Men’s high-risk diseases with elevated transaminases and AIDS mostly. Pre-pregnancy health guidance and treatment of these diseases can effectively reduce birth defects. Conclusion The national free pre-pregnancy eugenics health check is an important means of first-level intervention of birth defects, which helps to improve the quality of perinatal health care and deserves further application and promotion.