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目的:分析和探讨消化内科临床上对于肠梗阻患者采用生长抑素进行治疗的效果,以期为该方法的临床推广提供数据参考。方法:对2012年07月至2015年03月我院消化道内科收治的200例肠梗阻患者临床资料进行回顾性分析,根据患者入院时病例号,采用随机数表的方法将其随机分为保守治疗组合生长抑素治疗治疗组,前者采用肠外营养支持、减压、抗感染以及纠正电解质治疗等,后者在此基础上联合给予生长抑素进行治疗,比较两组患者临床疗效。结果:两组患者经过临床治疗,保守治疗组48h肠排气率为76.00%(76/100),生长抑素治疗组48h肠排气率为93.00%(93/100),差异极显著(P<0.01);保守治疗组治疗后C反应蛋白含量为(73.2±6.5)mg/L,生长抑素治疗组治疗后C反应蛋白含量为(37.6±1.88)mg/L,两组差异极显著;保守治疗组患者平均住院时间为(13.4±2.3)d,生长抑素治疗组平均住院时间为(8.6±1.5)d,差异显著(P<0.05)。结论:本研究结果表明,消化道内科临床上对于肠梗阻患者在保守治疗的基础上联合使用生长抑素的疗效显著,该方法能显著改善患者临床症状,缩短患者的住院时间,减轻由于疾病给患者带来的生理和心理上的压力,因此值得临床推广使用。
OBJECTIVE: To analyze and discuss the clinical effect of somatostatin treatment for patients with intestinal obstruction in the department of Gastroenterology, in order to provide data reference for the clinical promotion of this method. Methods: The clinical data of 200 cases of intestinal obstruction admitted to Department of Gastroenterology from July 2012 to March 2015 in our hospital were retrospectively analyzed. According to the case number of patients on admission, they were randomly divided into conservative Treatment combination of somatostatin treatment group, the former using parenteral nutrition support, decompression, anti-infective and correct electrolyte treatment, the latter on the basis of combination of somatostatin for treatment, the clinical efficacy of two groups were compared. Results: After two groups of patients underwent clinical treatment, the rate of intestinal excretion was 76.00% (76/100) in the conservative treatment group and 93.00% (93/100) in the 48h group. The difference was significant (P <0.01). The content of C-reactive protein in the conservative treatment group was (73.2 ± 6.5) mg / L after treatment, and the level of C-reactive protein in the somatostatin treatment group was (37.6 ± 1.88) mg / L after treatment. The average length of stay in patients in the conservative treatment group was (13.4 ± 2.3) days, and the average duration of stay in the patients treated with somatostatin was (8.6 ± 1.5) days, with significant difference (P <0.05). Conclusion: The results of this study show that gastrointestinal medicine clinically for patients with intestinal obstruction in the conservative treatment based on the combination of somatostatin significant effect, the method can significantly improve the clinical symptoms, shorten the hospital stay of patients and reduce the disease due to Patients with physical and psychological stress, it is worth promoting the use of the clinic.