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目的探讨卡前列素氨丁三醇预防高危妊娠产妇产后出血的临床疗效。方法选取2013年3月—2015年5月台安县妇幼保健院收治的73例高危妊娠产妇,随机分为研究组37例和对照组36例。两组产妇均行剖宫产,对照组给予米索前列醇和缩宫素预防产后出血,研究组给予卡前列素氨丁三醇和缩宫素预防产后出血,比较两组产妇产后2、24h出血量及输血、产后出血、子宫切除发生率。结果研究组产妇产后2、24h出血量少于对照组,产妇输血、产后出血发生率均低于对照组,差异有统计学意义(P<0.05)。结论卡前列素氨丁三醇预防高危妊娠产妇产后出血的疗效显著,可有效减少产后出血量,降低产后出血发生率,保障母婴生命安全。
Objective To investigate the clinical efficacy of carboprost trometamol in preventing postpartum hemorrhage in high-risk pregnancies. Methods From March 2013 to May 2015, 73 maternal high risk pregnancies in Tai’an MCH hospital were randomly divided into study group (37 cases) and control group (36 cases). The two groups of women were cesarean section, the control group was given misoprostol and oxytocin to prevent postpartum hemorrhage. The study group was given carboprost trometamol and oxytocin to prevent postpartum hemorrhage. And blood transfusion, postpartum hemorrhage, the incidence of hysterectomy. Results The bleeding volume of postpartum women in study group was less than that in control group at 2 and 24 hours. The incidences of blood transfusion and postpartum hemorrhage were all lower in study group than in control group (P <0.05). Conclusion The effect of carboprost trometamol in preventing postpartum hemorrhage in high risk pregnancy is significant, which can effectively reduce the amount of postpartum hemorrhage, reduce the incidence of postpartum hemorrhage and ensure the safety of mother and infant.