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1994-1995年,对26例具有慢性消化道症状的儿童进行临床观察。男17例,女9例;年龄3-12岁;病 程最短1月。最长1(1/2)年。其中反复腹痛23例,呕吐15例,纳差14例.消瘦及消化不良18例。全部病例均排除了胃肠痉挛、肠虫症、腹型癫痫、结核、肝炎及药物影响等。对这些患儿进行胃镜检查,结果发现24例有慢性胃炎改变。对这24例患儿进行胃粘膜活检,用尿素酶HP试纸法检测HP,结果20例阳性。阳性率83.3％;同时,对这24例患儿用ELISA法检测血清抗HPIgG抗体,19例阳性,阳性率79.1％,经卡方检验,这两种检测方法的结果无显著性差异(x~2=O.02,P>O.05)。对患儿进行分组研究,发现3-6岁患儿尿素酶HP试纸法阳性率为75.O％,ELISA法
In 1994-1995, 26 children with chronic gastrointestinal symptoms were clinically observed. 17 males and 9 females; aged 3-12 years; the shortest course of January. Up to 1 (1/2) year. Including repeated abdominal pain in 23 cases, vomiting in 15 cases, anorexia in 14. Emaciation and indigestion in 18 cases. All cases were ruled out gastrointestinal spasm, intestinal worms, abdominal epilepsy, tuberculosis, hepatitis and drug effects. Gastroscopy on these children found that 24 patients had chronic gastritis. Gastric mucosal biopsy was performed on these 24 patients, and HP was detected by urease HP test strips. The results were positive in 20 cases. Positive rate of 83.3%; the same time, the 24 cases of children with anti-HPIgG antibody by ELISA, 19 positive, the positive rate of 79.1%, by chi-square test, the two test results showed no significant difference (x ~ 2 = O.02, P> O.05). Group study of children found that 3-6-year-old children with urease HP test strip positive rate of 75.0%, ELISA