目的调查不动杆菌和铜绿假单胞菌肺炎的临床特点及细菌耐药。方法回顾性分析46例不动杆菌和铜绿假单胞菌引起的肺炎的临床资料和细菌耐药。结果这两种细菌引起的肺炎无特异性。两者基础疾病,主要为慢性阻塞性肺疾病(COPD),其次为恶性肿瘤、心功能不全、脑中风及支气管扩张。两者主要症状是发热(73%),咳嗽(92%),氯急。胸部X线表现肺部间质病变13例。药敏结果显示出这两种细菌多重耐药,但阿米卡星,哌拉西林、环丙沙星、诺氟沙星、头孢曲松、头孢哌酮为较敏感的抗生素。结论不动杆菌和铜绿假单胞菌引起的肺炎之间无特异性临床特点。两菌肺炎患者的气急病人因以控制感染为主,诊断依靠病原学并结合临床及X线检查,治疗应根据药敏并联合应用抗生素。 Objective To investigate the clinical features and bacterial resistance of Acinetobacter and Pseudomonas aeruginosa pneumonia. Methods Retrospective analysis of 46 cases of Acinetobacter and Pseudomonas aeruginosa pneumonia caused by clinical data and bacterial resistance. The results of these two bacteria caused by non-specific pneumonia. The two underlying diseases were mainly chronic obstructive pulmonary disease (COPD), followed by malignancy, cardiac insufficiency, stroke and bronchiectasis. The main symptoms of both were fever (73%), cough (92%), and chlorine rush. Chest X-ray findings of pulmonary interstitial lesions in 13 cases. Susceptibility results showed that these two bacteria were multi-drug resistant, but amikacin, piperacillin, ciprofloxacin, norfloxacin, ceftriaxone and cefoperazone were more sensitive antibiotics. Conclusion Acinetobacter and Pseudomonas aeruginosa pneumonia caused by no specific clinical features. Two bacterial pneumonia patients with acute respiratory failure due to infection control, diagnosis depends on the combination of etiology and clinical and X-ray examination, the treatment should be based on drug sensitivity combined with antibiotics.