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目的探讨吉兰巴雷综合征感觉变异型患者的临床特点及诊断。方法分析4例吉兰巴雷综合征感觉变异型患者的临床表现、以及神经电生理及脑脊液的检测结果。结果4例患者均以感觉异常为首发症状,其中2例发生于双下肢,1例发生于上肢,另1例四肢均出现感觉异常;脑脊液蛋白含量范围在0.45～0.55g/L3例,0.55～0.65g/L1例。测定4例患者神经传导速度,16条运动神经末端潜伏期延长12条(75%),运动神经传导速度减慢13条(81%),F波潜伏期延长或消失12条(75%);12条感觉神经的神经传导速度均减慢(100%)。传导阻滞和/或一过性离散异常6条(50%)。结论吉兰巴雷综合征感觉变异型患者临床上因无肢体瘫痪,仅出现肢体感觉异常,其诊断有赖于神经电生理及脑脊液的检查。
Objective To investigate the clinical features and diagnosis of patients with degeneration of Guillain-Barre syndrome. Methods The clinical manifestations, neuroelectrophysiology and cerebrospinal fluid test results of 4 patients with sensory variant of Guillain-Barre syndrome were analyzed. Results All 4 patients had sensory abnormality as the first symptom. Among them, 2 cases occurred in both lower extremities, 1 case occurred in the upper extremities and the other 4 cases had sensory abnormalities. The CSF protein content ranged from 0.45 to 0.55 g / L3, 0.65g / L1 Example. The nerve conduction velocity was measured in 4 patients. The latency of 16 motor neurons was prolonged by 12 (75%), the motor nerve conduction velocity was reduced by 13 (81%), and the latency of F wave was prolonged or disappeared by 12 (75%). Sensory nerve nerve conduction slows (100%). Blocking and / or transient discrete abnormalities 6 (50%). Conclusion Guillain-Barre syndrome patients with sensory variability clinically because of no limb paralysis, only the emergence of limb sensory abnormalities, the diagnosis depends on neuroelectrophysiology and cerebrospinal fluid examination.