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变态反应性鼻炎(AR)以发作性鼻痒、鼻塞、喷嚏和流清水样鼻涕为主要症状,其发病机制目前仍然不完全清楚。目前认为,细胞因子在AR的病程中发挥了极其重要的作用。糖皮质激素对AR的治疗效果早已受到学者的肯定,但其治疗AR的机制目前仍不完全清楚。本文以AR患者为对象,通过观察AR患者丙酸倍氯米松鼻喷雾剂治疗前后外周血IL-5、IL-8、IL-10的含量变化,探讨丙酸倍氯米松鼻喷雾剂治疗AR的可能机制,现报道如下。1资料和方法1.1临床资料2008年8月～2010年3月,选择在我院就诊治疗的AR病例40例(AR组),AR的诊断符合中华医学会耳鼻咽喉科分会(2004年,兰州)的相关标准。AR组男
Allergic rhinitis (AR) with the onset of nasal itching, stuffy nose, sneezing and watery nasal discharge as the main symptoms, the pathogenesis is still not fully understood. At present, cytokines play an extremely important role in the course of AR. The therapeutic effect of glucocorticoids on AR has long been recognized by scholars, but its mechanism of AR treatment is still not fully understood. In this paper, AR patients as the object, by observing AR patients with beclometasone nasal spray before and after treatment of peripheral blood levels of IL-5, IL-8, IL-10 content to explore the beclometasone dipropionate nasal spray treatment of AR Possible mechanisms are reported below. 1 Materials and Methods 1.1 Clinical data August 2008 ~ March 2010, AR patients treated in our hospital selected 40 cases (AR group), AR diagnosis in line with the Chinese Medical Association Otolaryngology Branch (2004, Lanzhou) The relevant standards. AR group of men