12名有吸烟习惯和8名不吸烟的健康人参加双盲安慰剂对照研究,以确定吸烟对H_2-受体拮抗剂法莫替丁的影响。在吸烟者中,吸烟统一在给药前1小时或给药后2小时开始或禁烟。胃内pH浓度是用标准pH Twelve blind placebo-controlled studies of 12 smokers and 8 non-smokers were performed to determine the effect of smoking on the H 2 -receptor antagonist famotidine. In smokers, smoking is uniform at 1 hour before administration or 2 hours after administration. Intragastric pH is measured using standard pH