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美国波士顿消息:最近进行的Leuprolide多中心研究表明,它可使妇科医生们推迟或避免对年轻子宫肌瘤患者施行子宫切除术。 Leuprolide是含9个氨基酸的垂体受体兴奋剂,它先增加黄体生成素(LH)和促卵泡素(FSH)生成1～3周,以后降低两个激素的含量和分泌,致使卵巢得不到刺激,最后抑制卵巢产生雌激素,月经停止。 1983年William F Crowley Jr等在马州总医院首先用LHRH兴奋剂成功治疗一例25岁
Boston, United States: Recent Leuprolide multicenter studies have shown that gynecologists can delay or avoid hysterectomy in patients with young uterine fibroids. Leuprolide is a 9-amino acid pituitary receptor agonist. It first increases the production of luteinizing hormone (LH) and follicle stimulating hormone (FSH) for 1-3 weeks, then decreases the content and secretion of two hormones, resulting in no stimulation of the ovary. Finally, ovarian suppression of estrogen, menstruation stopped. In 1983, William F Crowley Jr et al first successfully treated a case of 25-year-old with LHRH agonist at the Mazhou General Hospital