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对3个不同类型的献血村(献浆为主村、献全血兼献浆村和献全血为主村)进行了HCV感染状况的血清流行病学调查.结果,抗-HCV标化阳性率分别为14.65%、1.39%和0.40%。3个村中献浆血员抗-HCV阳性率分别为67.20%(84/125)、33.33%(14/42)和13.33%(2/15),献全血血员分别为5.33%(4/75)、0.33%(1/306)和0.65%(1/153);受血者分别为66.67%(2/3)、0.00%(0/4)和14.29%(1/7);其他人群分别为1.84%(8/35)、0.15%(1/652)和0(0/688)。献浆为主村各类人群抗-HCV阳性率显著高于其它两村.结果表明,献浆和输血是HCV传播的主要因素.献浆为主村可能还存在HCV母婴、家庭内接触和医源性传播。因此,控制HCV感染应采取以献血员管理为主的综合性预防措施。
Serological epidemiological survey of HCV infection status was conducted in 3 different types of donated blood donated villages (donated primary village, donated whole blood and donated plasma and donated whole blood as the main village). As a result, the positive rates of anti-HCV standardization were 14.65%, 1.39% and 0.40% respectively. The positive rate of anti-HCV in blood plasma in three villages were 67.20% (84/125), 33.33% (14/42) and 13.33% (2/15) Respectively, which were 5.33% (4/75), 0.33% (1/306) and 0.65% (1/153), respectively. The recipients were 66.67% (2/3), 0.00 % (0/4) and 14.29% (1/7) respectively; the other groups were 1.84% (8/35), 0.15% (1/652) and 0 (0/688) respectively. Anti-HCV positive rate was significantly higher than other two villages. The results show that donation and blood transfusion are the main factors of HCV transmission. The main village to offer pulp may also exist HCV mother and child, family contacts and iatrogenic transmission. Therefore, the control of HCV infection should take a comprehensive preventive measures dominated by blood donors.