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目的:观察牛痘疫苗致炎兔皮提取物注射液治疗糖尿病周围神经病变的临床疗效。方法:用牛痘疫苗致炎兔皮提取物注射液治疗30例糖尿病周围神经病变,与26例甲钴胺治疗糖尿病周围神经患者作为对照。发现牛痘疫苗致炎兔皮提取物注射液可以不同程度减轻患者肢体麻木、疼痛等临床症状,尤其对痛性病变改善较明显。结果:观察组疗效有效率为90.0%,对照组有效率为53.85%,观察组明显高于对照组(P<0.05),差异有统计学意义。且在治疗过程中没有明显副作用,是安全有效的。结论:牛痘疫苗致炎兔皮提取物注射液是治疗糖尿病周围神经病变的一种有效药物。
Objective: To observe the curative effect of injecting vaccinia vaccination rabbits skin extract on diabetic peripheral neuropathy. Methods: 30 cases of diabetic peripheral neuropathy were treated with injection of vaccinia vaccination rabbits skin and 26 cases of mecobalamin treatment of diabetic peripheral neuropathy as control. Found that vaccinia vaccination Rabbit skin extract injection can relieve numbness, pain and other clinical symptoms in patients with varying degrees, especially for the improvement of painful lesions more obvious. Results: The effective rate of the observation group was 90.0%, the effective rate of the control group was 53.85%, the observation group was significantly higher than the control group (P <0.05), the difference was statistically significant. And no obvious side effects in the course of treatment, is safe and effective. Conclusion: The vaccination of vaccinia vaccination rabbit skin extract is an effective treatment of diabetic peripheral neuropathy.